Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Pleural effusion
ADR ID BADD_A03461
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.05      Pleural disorders
22.05.02      Pneumothorax and pleural effusions NEC
22.05.02.002      Pleural effusion
Description A disorder characterized by an increase in amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough and marked chest discomfort. [CTCAE] Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself. [MeSH]
MedDRA Code 10035598
MeSH ID D010996
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Effusion pleural | Intrapleural fluid retention of | Other specified forms of pleural effusion, except tuberculous | Pleural effusion | Unspecified pleural effusion | Pleural fluid exudate | Pulmonary effusion | Pleural effusion recurrent | Trapped lung | Bilateral pleural effusion | Pleural Effusion | Effusion, Pleural | Effusions, Pleural | Pleural Effusions
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02459Dalteparin0.012704%
BADD_D02460Ganirelix0.005881%
BADD_D02464Fingolimod--
BADD_D02467Naloxegol0.002440%
BADD_D02470Nintedanib--
BADD_D02473Sodium chloride--
BADD_D02476Polyethylene glycol0.000334%
BADD_D02480Alectinib0.003197%
BADD_D02483Ribociclib0.002664%
BADD_D02486Niraparib0.001332%
BADD_D02492Deflazacort--
BADD_D02498Abemaciclib--
BADD_D02500Alpelisib--
BADD_D02503Telotristat ethyl-
BADD_D02504Lorlatinib0.002664%
BADD_D02505Gilteritinib0.000799%
BADD_D02508Edaravone0.002614%
BADD_D02510Rucaparib0.003730%
BADD_D02517Enasidenib0.000533%
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